Pcr Thermal Cyclers
PCR thermal cyclers are essential laboratory equipment designed for amplification and analysis of DNA through the polymerase chain reaction process. These devices precisely regulate temperature cycles to enable accurate denaturation, annealing, and extension of DNA strands, making them indispensable in molecular biology, medical diagnostics, and research applications. Their versatility allows use in genetic testing, forensics, infectious disease detection, and vaccine development.
The functionality of PCR thermal cyclers ranges from basic models suitable for routine tests to advanced systems featuring gradient temperature control and high-throughput capabilities. Laboratories benefit from these devices’ reliability, ease of programming, and uniform heating, which guarantee reproducible results. With ongoing technological advancements, modern thermal cyclers integrate software for automation and data analysis, optimizing laboratory workflow and productivity across various scientific disciplines.
What You Need to Know Before Selecting a PCR Thermal Cycler and Making an Investment
Key Factors to Consider
When choosing a PCR thermal cycler, key factors include temperature accuracy, uniformity, and ramp rates, which directly affect the efficiency and reliability of DNA amplification. It’s vital to evaluate the control software’s usability and programmability to ensure seamless protocol adjustments and reproducibility. Compatibility with various tube formats and plates is also essential to suit different throughput needs and sample sizes.
Another crucial consideration is the device’s maintenance and support services. Efficient diagnostics and easy access to technical assistance reduce downtime and ensure the instrument operates at peak performance. Additionally, noise levels and size may be important for lab environments. Energy consumption and integration with laboratory information management systems (LIMS) can further improve operational efficiency.
Price Range in the Market
PCR thermal cyclers can vary significantly in price depending on features such as gradient capability, block capacity, and automation options. Entry-level models suitable for basic research typically fall into a lower price range, whereas advanced systems designed for clinical diagnostics or high-throughput screening demand higher investment. Accessories and software packages may also impact the overall cost.
It is important to consider not only the initial purchase price but also associated costs like consumables, service contracts, and potential upgrades. The market offers a broad spectrum of choices, from compact benchtop units to fully integrated thermal cyclers with real-time PCR functionality, each priced according to their technical specifications and intended laboratory applications.
Quality-Price Ratio
Assessing quality-price ratio involves analyzing the balance between device durability, feature set, and performance reliability relative to its cost. Investing in well-known, reputable brands often ensures better long-term value due to robust support and fewer operational issues. Conversely, lower-cost options may initially save funds but could increase maintenance expenses or limit throughput capabilities.
Optimal quality-price balance is achieved by selecting thermal cyclers that meet specific laboratory needs without unnecessary complexity. Evaluating user feedback, warranty conditions, and energy efficiency aids in identifying models that sustain performance while controlling operational costs. This strategic approach maximizes return on investment and laboratory productivity.
Expected Lifespan Based on Use and Maintenance
The lifespan of PCR thermal cyclers depends largely on usage intensity, maintenance routines, and adherence to operating guidelines. Regular calibration, cleaning, and prompt servicing extend functional years. Well-maintained units from trusted manufacturers can last over a decade, retaining accuracy essential for critical molecular assays.
Improper maintenance, environmental factors like humidity or temperature fluctuations, and improper handling can shorten the instrument’s life expectancy. Training laboratory personnel in correct usage and preventive care protocols ensures reliable performance and mitigates premature equipment failure risks.
KALSTEIN PCR THERMAL CYCLERS
Among many products, at Kalstein you can find the ideal thermal cycler for your Laboratory
If you are unsure which PCR thermal cycler to purchase, we offer extensive guidance and a variety of reliable models tailored to your laboratory’s specific requirements, ensuring you make an informed and effective investment in molecular diagnostics technology.
Real-time PCR System YR01868
The Real-Time PCR Thermocycler YR01868 is a state-of-the-art device designed to meet the needs of small and medium-sized…
Real-time PCR System YR01867
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Real-time PCR System YR06248 // YR06249
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Our PCR thermal cycler best seller
The Real-Time PCR Thermocycler YR01868 is a state-of-the-art device designed to meet the needs of small and medium-sized laboratories, as well as mobile labs and field testing. With its innovative optical technologies and powerful software, this thermocycler ensures reliability and efficiency in every test. Capable of processing up to 48 samples in just 2 seconds, it significantly reduces testing time, optimizing productivity and improving result accuracy.
The price of the YR01868 Thermocycler ranges from $14,770 to $14,780 USD, depending on the supplier and additional options, such as technical support and specialized consumables. This high-quality, high-performance system is available for laboratories seeking a portable, efficient, and easy-to-use thermocycler, ideal for improving productivity in PCR research.
| Model | YR01868 |
| Throughput | ene-48 |
| Fluorescence Channels | 2 |
| Fluorescence Scanning Time | 2s |
| Dye Compatibility | Channel 1: FAM, SYBR Green I , SYTO 9, Eva Green, LC Green |
| Channel 2: HEX, VIC, TET, JOE | |
| Optical System | |
| Light Source | High-brightness, long life and maintenance-free LED light source |
| Detector | Photodiodes (PDs) |
| Excitation Range | CH1: 470nm CH2:523nm CH3:570nm CH4:638nm |
| Detection Range | CH1:525nm CH2:564nm CH3:610nm CH4:685nm |
| Fluorescence Dynamic Range | Adjustable |
| Sample Dynamic Range | From 101 to 1010copies |
| Thermal Black | |
| Heating Method | Peltier |
| Heating Rate | ≥8.0 ℃/s ℃ |
| Cooling Rate | ≥6.2 ℃/s |
| Temperature Accuracy | ≤0.1 ℃ |
| Gradient Range | 1℃-40 ℃ |
| Gradient Block | 8 row |
| Special Temperature Protocol | Thermal gradients PCR, long PCR, Touch Down PCR |
| Sample Testing Linearity and Repeatability | Linear correlation: /r/ ≥ 0.999 |
| Repeatability: cycle threshold (Ct) value CV≤0 0.5% | |
| Software Functions | |
| Control Modes | Model1: 7 inch touch screen |
| Mode 2: PC direct control | |
| Power Failure Protection | Automatically start running experiments after power supply, no need to wait PC software |
| Data Storage and Transmission | Upload and download through USB disk. 1000 results can be stored in machine |
| Reporting Function | Templates reserved; customized experiment report |
| Key Applications | Relative quantification, absolute quantification, melting curve analysis ,SNP analysis |
| Others | |
| Operating System for PC | Win7/Win10/Win11 |
| Power Supply and Power Consumption | AC 100-240V,S0-60HZ; 600VA |
| Weight | 11 Kg (net) |
| Instrument Dimension | 260*400*260mm (W*L*H) |
| Suitable Consumables | 0.2mL clear non-skirt 48-WELL plates, 8>tube strips, single tubes, etc. |
Key elements impacting thermal cycler performance and accuracy.
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PCR Thermal Cyclers on Sale
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Automatic Nucleic Acid Extractor YR01869-2
Biolum Portable ATP Hygiene Monitoring System YR06071
Real-time PCR System YR06248 // YR06249
Kalstein offers innovative, reliable thermal cyclers for molecular labs.
Discover our comprehensive guides on choosing, operating, and maintaining PCR thermal cyclers effectively in your laboratory environment.
We provide expert advice and detailed recommendations to help you select the perfect PCR thermal cycler, maintain its optimal function, and enhance your laboratory’s molecular biology capabilities seamlessly.
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FAQs
The delivery time for your Kalstein product depends on the following:
- Whether the equipment of your interest is in stock or if it needs to be manufactured.
- The type of freight chosen: air or maritime.
- Equipment in stock:
– Delivery Time (Air): 15-30 days.
– Delivery Time (Maritime): 45-60 days.
- Equipment not in stock:
– Delivery Time (Air): 30-60 days.
– Delivery Time (Maritime): 60-90 days.
You can make your purchase through:
- Email: [email protected]
- Phone: +33 (0) 1 70 39 26 50
- E-commerce: Through Kalstein’s official country website.
At Kalstein, we provide clients with training and technical support via online methods. You can access our induction videos, technical assistance, and expert guidance provided by the Kalstein team through our YouTube channel (Kalstein English). HERE.